Adjunctive Sitagliptin Therapy in Postoperative Cardiac Surgery Patients: A Pilot Study

Table 1

Baseline patient profiles and operative characteristics.

Variable	Sitagliptin; (𝑛=30)	Placebo; (𝑛=32)	𝑃 value
Sex, male/female, 𝑛	21/8	27/5	0.255
Mean age, years	62.9 ± 9.6	66.1 ± 10.3	0.222
Height (inches)	67.5 ± 2.4	68.5 ± 3.6	0.241
Weight (kg)	93.1 ± 20.5	94.2 ± 18.0	0.822
Cardiovascular risk factors, 𝑛 (%)
History of stroke	3	1	0.255
History of CAD	1	0
Oral antihyperglycemics
Metformin, 𝑛 (%)	48.1%	38.7%	0.469
Sulfonylureas, 𝑛 (%)	25.9%	25.8%	0.992
Thiazolidinedione, 𝑛 (%)	7.4%	16.1%	0.309
Preoperative A1c, %	7.21	7.27	0.879
Type of procedure, 𝑛 (%)			0.282
CABG only	82.8%	84.4%
CABG + valve	6.9%	0%
Mean length of pump time, minutes	95.3 ± 30.9	88.4 ± 21.2	0.317
Mean length of ischemic time, minutes	67.2 ± 23.2	65.1 ± 17.9	0.707