Gamma Knife Radiosurgery for Acromegaly

Table 1

Studies of GKS for acromegaly.

Study	No. of patients	Mean follow-up (mos.)	Dose (Gy)	No. of remission (%)
Iwai et al., 2010 [42]	26	84	20.2	10 (38)
Ronchi et al., 2009 [43]	28	103	20	19 (96)
Swords et al., 2009 [44]	10	38.5	10	3 (30)
Wan et al., 2009 [45]	103	67	21.4	38 (37)
Jagannathan et al., 2009 [46]	95	57	22	50 (53)
Losa et al., 2008 [47]	83	69	25	50 (60)
Pollock et al., 2008 [48]	27	48	20	18 (67)
Vik-Mo et al., 2007 [34]	53	66	26.5	9 (17)
Ježková et al., 2006 [49]	96	54	32	48 (50)
Castinetti et al., 2005 [50]	82	49.5	25.7	14 (17)
Kobayashi et al., 2005 [40]	67	63	18.9	7 (10)
Attanasio et al., 2003 [51]	30	46	20	7 (23)
Choi et al., 2003 [52]	12	42.5	28.5	6 (50)
Jane Jr. et al., 2003 [53]	64	>18	15	23 (36)
Petrovich et al., 2003 [54]	6	41	15	6 (100)
Ikeda et al., 2001 [55]	17	56	25	14 (82)
Fukuoka et al., 2001 [56]	9	42	20	4 (44)
Izawa et al., 2000 [57]	29	>6	22.5	12 (41)
Shin et al., 2000 [58]	6	43	34.4	4 (67)
Zhang et al., 2000 [59]	26	36	31.3	25 (96)
Inoue et al., 1999 [60]	12	>24	20.9	7 (58)
Kim et al., 1999 [61]	2	12	22	0 (0)
Kim et al., 1999 [62]	11	27	28.7	5 (45)
Mokry et al., 1999 [63]	10	46	16	4 (40)
Lim et al., 1998 [64]	16	25.5	25.4	6 (38)
Martinez et al., 1998 [65]	7	36	24.7	6 (86)
Morange-Ramosa et al., 1998 [66]	15	20	28.7	3 (20)
Pan et al., 1998 [67]	15	29	28.6	15 (100)
Park et al., 1996 [68]	7	15	27.1	4 (57)
Total	964			417 (43)