Gestational Diabetes and Thyroid Autoimmunity

Table 1

Clinical characteristics and laboratory data of the four groups of women evaluated.

	Groups
	A1 (𝑛=91)	A2 (𝑛=35)	B1 (𝑛=38)	B2 (𝑛=31)
Mean age (years)	33±10	29±11	40±11	40±6
Time from delivery (range, months)	—	—	18–120	18–96
BMI at OGTT	29.8±4.0	28.1±4.7	27.2±2.2	—
BMI at follow-up	—	—	24.1±2.8	23.5±3.7
GAD65-Ab positivity [n (%)]	3 (3.3)	0	2 (5.3)	0
Mean FT4 (ng/dL)	0.82±0.13	0.83±0.09	0.93±0.21	0.92±0.17
Mean TSH (mIU/L)	1.46±1.02	1.90±1.4	2.45±4.32	1.44±0.92
TSH < 0.4 mIU/L [n (%)]	8 (8.8)	2 (5.7)	5 (13.1)	2 (6.5)
TSH > 4.2 mIU/L [n (%)]	2 (2.2)	2 (5.7)	4 (10.5)	1 (3.2)
Overall abnormal TSH [n (%)]	10 (11.0)	4 (11.4)	9 (23.7)*	3 (9.7)
Thyroid Ab positivity [n (%)]	16 (17.6)	5 (14.4)	12 (31.6)*	3 (9.7)
Abnormal TSH + thyroid Ab positivity [n (%)]	3 (3.3)	0 (−)	7 (18.4)**	1 (3.2)

^∗𝑃<0.05 versus groups A1 and B2; ^∗∗𝑃<0.05 versus groups B2 and 𝑃<0.001 versus group A1. Where indicated, data are means ± SD.