International Journal of Endocrinology / 2013 / Article / Fig 1

Review Article

The Endocannabinoid System and Sex Steroid Hormone-Dependent Cancers

Figure 1

Synthesis of N-arachidonoylethanolamine (AEA). N-acyltransferase (NAT) catalyzes the transfer of arachidonic acid (AA) from phosphatidylcholine (PC) to phosphatidylethanolamine (PE) to form N-arachidonoyl-phosphatidylethanolamine (NAPE). NAPE is then converted into AEA in a one-step hydrolysis reaction catalyzed by the NAPE-specific phospholipase D (NAPE-PLD).

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