Evaluation of Serum 25-Hydroxyvitamin D as a Predictor of Carotid Intima-Media Thickness and Carotid Total Plaque Area in Nonsmokers: The Tromsø Study

Table 4

Odds ratios (OR) and their respective 95% confidential intervals for the association between serum 25(OH)D and levels of mean IMT and TPA in men and women, using multinomial logistic regression. The 4th Tromsø Study, 1994-1995.

Multivariate models	Men, 𝑛=1994
	Mean IMT quartiles, mm				TPA groups, mm^2
	<0.76	0.76–0.87	0.88–1.00	>1.00	No plaques	<11.37	11.37–23.89	>23.89
Model 1	1.00	1.11 (0.98, 1.26)	1.03 (0.90, 1.17)	1.14* (1.00, 1.30)	1.00	1.09 (0.96, 1.23)	1.09 (0.97, 1.24)	1.03 (0.91, 1.17)
Model 2	1.00	1.14 (0.99, 1.30)	1.12 (0.96, 1.30)	1.30** (1.12, 1.51)	1.00	1.06 (0.93, 1.20)	1.10 (0.96, 1.25)	1.08 (0.94, 1.23)
Multivariate models	Women, 𝑛=2200
	Mean IMT quartiles, mm				TPA groups, mm^2
	<0.72	0.72–0.81	0.82–0.93	>0.93	No plaques	<9.42	9.42–18.07	>18.07
Model 1	1.00	0.90 (0.80, 1.01)	0.89 (0.80, 1.01)	0.77 (0.68, 0.86)**	1.00	0.93 (0.82, 1.06)	0.98 (0.87, 1.11)	0.89 (0.78, 1.01)
Model 2	1.00	1.02 (0.90, 1.16)	1.12 (0.98, 1.28)	1.10 (0.96, 1.28)	1.00	1.00 (0.88, 1.14)	1.12 (0.98, 1.27)	1.15* (1.01, 1.33)

Model 1. Serum 25 (OH) D adjusted for season when vitamin D samples were obtained.
Model 2. Serum 25 (OH) D adjusted for season of sampling, age, BMI, SBP, and total cholesterol.
* 𝑃<0.05.
** 𝑃<0.001.