Research Article

Improved Glucose-Stimulated Insulin Secretion by Selective Intraislet Inhibition of Angiotensin II Type 1 Receptor Expression in Isolated Islets of db/db Mice

Figure 2

Effects of AT1R silencing on AT1R expression. (a) Islets of db/db mice were transfected with Ad-si AT1R, Ad-siControl, or Mock and cells were cultured for 72 h prior to quantitative RT-PCR. Results are represented as mean ± SD for six independent experiments. * versus Ad-siControl. (b) Islets of db/db mice were transfected with Ad-si AT1R, Ad-siControl, or Mock and cells were cultured for 72 h prior to quantitative immunoblot evaluation. Results are represented as mean ± SD for six independent experiments. * versus Ad-siControl.
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