Clinical Study

Association between TCF7L2 Genotype and Glycemic Control in Diabetic Patients Treated with Gliclazide

Figure 1

Convergence of the sulfonylurea and incretin pathways on insulin secretion via Epac2 [14]. cAMP: cyclic adenosine monophosphate; KATP: ATP-dependent potassium channel; VDCC: voltage dependent calcium channel; Epac2: exchange protein activated by cAMP 2; Rap1: Ras-like guanosine phosphatase.
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