Use of Radiofrequency Ablation in Benign Thyroid Nodules: A Literature Review and Updates

Table 1

Result of volume reduction in patients who underwent radiofrequency ablation for cold thyroid nodule.

	Number of nodule/patients	Solid component	Follow-up duration (months)	Electrode type	Number of session (mean)	Mean initial volume (mL)	Volume reduction at the 1st month (%)	Volume reduction at the last follow-up (%)
Sung et al. [11]	21/21	<10%	1–6	Internally cooled	1–3 (1.67)	10.2		92
Deandrea et al. [22]	10/9	>30%	6	Multitined expandable	1	38.7	31.7	46.3
Spiezia et al. [23]	66/66	>30%	12–24	Multitined expandable	1–3 (1.4)	21.1	43.7	76.6
Lee et al. [40]	27/27	10–50%	6–38	Internally cooled	1–4 (1.6)	14		97
Jang et al. [19]	20/20	<50%	6–43	Internally cooled	1-2 (1.1)	11.3		92
Baek et al. [17]	15/15	>50%	6–8	Internally cooled	1	7.5	49	80
Ha et al. [5]	14/11	>50%	7–92	Internally cooled		9.7		87.2
Huh et al. [41]	15/15; 15/15	>50%	6	Internally cooled	1; 2	13.3; 13.0	40; 42.7	70.2; 78.3
Faggiano et al. [24]	10/10	>70%	12	Multitined expandable	1	13.3	36.5	84.9
Kim et al. [36]	35/30	0–100%	1–18	Internally cooled	1	6.3	47	64
Jeong et al. [15]	302/236	0–100%	1–41	Internally cooled	1–6 (1.4)	6.1	58	84
Lim et al. [20]	126/111	0–100%	36–81	Internally cooed	1–7 (2.2)	9.8		93.4