Establishing Reference Intervals for Bone Turnover Markers in the Healthy Shanghai Population and the Relationship with Bone Mineral Density in Postmenopausal Women
Table 4
Geometric means and (95% CI) for the age-specific measurements of bone turnover markers in healthy men.
Age
Number
-CTX (ng/mL)
P1NP (ng/mL)
OC (ng/mL)
PTH (pg/mL)
20–24
43
0.745* (0.464–1.024)
64.44* (41.81–87.05)
25.21* (17.57–28.86)
31.77 (25.61–39.94)
25–29
72
0.504* (0.415–0.551)
51.81* (43.42–60.20)
21.08* (18.12–24.06)
34.73 (31.14–38.33)
30–34
93
0.419* (0.353–0.482)
44.68* (38.25–51.10)
18.51* (15.97–21.05)
34.06 (30.46–37.67)
35–39
102
0.402 (0.333–0.470)
44.22 (37.64–57.01)
18.34 (15.66–21.02)
35.51 (32.40–38.62)
40–44
117
0.402 (0.318–0.485)
43.98 (36.78–51.78)
17.85 (14.89–20.79)
35.09 (31.89–38.29)
45–49
45
0.340* (0.252–0.428)
36.62* (29.37–43.88)
16.02* (11.97–20.05)
30.01 (25.92–34.20)
50–54
53
0.342* (0.267–0.414)
39.59* (32.23–46.93)
16.69* (13.72–19.65)
34.60 (30.86–38.35)
55–59
64
0.353* (0.278–0.427)
36.93* (30.62–43.23)
15.58* (13.07–18.09)
35.80 (31.57–40.02)
60–64
45
0.393* (0.276–0.508)
41.19* (31.63–50.13)
20.95* (16.32–25.66)
36.94* (31.27–42.60)
65–69
26
0.352* (0.218–0.485)
39.39* (27.48–50.87)
19.43* (12.28–25.51)
37.44* (30.58–44.31)
70–74
21
0.383* (0.167–0.598)
40.00* (26.65–53.33)
21.84* (15.95–27.73)
37.45* (30.52–44.38)
75–79
24
0.355* (0.208–0.501)
40.10* (25.60–54.69)
20.86* (14.72–27.00)
36.34* (29.98–42.70)
Reference valuea
226
0.400 (0.310–0.479)
44.01 (37.27–52.97)
18.01 (14.91–20.97)
33.92 (30.21–38.17)
All values are presented as the geometric means (95% CI).
*
versus reference values.
aReference values were calculated from the 35–45-year-old cohort as the geometric mean (95% CI).
