Multidisciplinary Approach to the Treatment of Obese Adolescents: Effects on Cardiovascular Risk Factors, Inflammatory Profile, and Neuroendocrine Regulation of Energy Balance

Table 3

Effects of interdisciplinary therapy in metabolic profile (factors associated with metabolic syndrome definition by International Diabetes Federation (IDF)).

Variables	Baseline	After therapy	𝑃 value	Δ value
Waist circumference (cm)	103.4±10.7	94.4±11.6	<0.001	−9.5±18.32
Glucose (mg/dL)	90.5±7.8	89.7±7.7	0.43	0.77±8.60
Insulin (µU/mL)	17.1±8.0	12.0±9.6	<0.001	−4.94±10.50
HDL-cholesterol (mg/dL)	43.7±8.6	45.3±9.2	<0.001	1.80±5.51
LDL-cholesterol (mg/dL)	102.4±27.4	94.0±24.0	<0.001	−9.98±17.54
VLDL-cholesterol (mg/dL)	21.3±9.4	17.8±8.5	<0.001	−3.44±8.06
Triglyceride (mg/dL)	111.2±64.2	88.9±42.6	<0.001	−21.27±52.50
HOMA-IR	3.8±2.0	2.7±1.7	<0.001	−1.13±3.00

HOMA-IR: homeostasis model assessment insulin-index resistance; HLD: high-density lipoprotein; LDL: low-density lipoprotein; VLDL: very-low-density lipoprotein. Reference values: glucose (60–110 mg/dL); insulin (<20 μU/mL); HOMA-IR (<2.0); total cholesterol (<170 mg/dL); Triglyceride (33–129 mg/dL); HDL cholesterol (>38 mg/dL); LDL cholesterol (<130 mg/dL); VLDL cholesterol (10–50 mg/dL) (2); statistical significance 𝑃≤0.05.