Research Article

Glucocorticoid-Induced Bone Loss Is Associated with Abnormal Intravertebral Areal Bone Mineral Density Distribution

Table 1

Descriptive measures for each group and pooled data, expressed as the mean (SD) for age, height, mass, and BMI and as the mean (95% CI) for FRAX data, -scores, and L3 area.

Descriptive measureGroupPooled
Primary osteoporosisGIOControl

 (% female)43 (95.3)13 (30.8)48 (83.3)104 (81.7)
Age (years)61.1 (5.0)63.7 (7.8)61.5 (5.6)62.1 (6.1)
Height (cm)163.1 (7.6)169.1 (8.7)166.8 (6.5)166.3 (7.6)
Mass (kg)61.8 (10.0)b,c75.6 (16.1)a71.9 (8.8)69.8 (11.6)
BMI (kg/m2)23.2 (3.0)b,c26.2 (3.7)a25.8 (2.8)25.1 (3.2)
FRAX major osteoporotic (%)4.5 (3.7 to 5.4)c6.0 (3.3 to 8.7)c2.6 (2.0 to 3.2)4.4 (3.0 to 5.8)
FRAX hip (%)1.1 (0.8 to 1.4)2.1 (0.8 to 3.4)c0.4 (0.1 to 0.7)1.2 (0.6 to 1.8)
-score PA spine (L1–4)−2.6 (−2.9 to −2.4)b,c−1.6 (−2.4 to −0.9)a,c0.0 (−0.2 to 0.3)−1.4 (−1.8 to −1.0)
-score total hip−2.0 (−2.2 to −1.8)b,c−1.3 (−1.9 to −0.8)a,c−0.2 (−0.4 to 0.1)−1.8 (−1.5 to −0.8)
L3 area (ROI 1) (cm2)8.8 (8.1 to 9.5)b11.1 (10.1 to 12.0)a9.9 (9.1 to 10.0)9.9 (9.1 to 10.5)

Significant difference compared to the primary osteoporosis group (); bsignificant difference compared to the GIO group (); csignificant difference compared to control group ().