The ETS-Domain Transcription Factor Elk-1 Regulates COX-2 Gene Expression and Inhibits Glucose-Stimulated Insulin Secretion in the Pancreatic β-Cell Line INS-1
Figure 1
Elk-1 upregulated COX-2 gene expression. (a and b) Elk-1 and COX-2 mRNA levels were determined by quantitative real-time RT-PCR. Relative mRNA expression was expressed as mean ± SEM. * versus control. (c) Elk-1 and COX-2 protein levels were assayed by Western blot analysis. β-actin levels served as internal control.
