Selective Determinants of Low Bone Mineral Mass in Adult Women with Anorexia Nervosa
Table 2
Serum and urinary measurements (mean ± SD, or median values). Patient’s characteristics by estrogen use and menstrual history.
Laboratory test
Normal range
All patients
Amenorrheic women1
Current estrogen use
Eugonadal women
Serum corrected calcium
[2.25–2.60 mmol/L]
64
2.35 ± 0 .09
2.34 ± 0.1
2.35 ± 0.1
2.36 ± 0.1
Serum phosphate
[0.80–1.4 mmol/L]
63
1.3 (0.3)
1.3 (0.2)
1.3 (0.2)
1.5 (0.4)
Serum creatinine
[35–88 µmol/L]
65
71.85 ± 11.32
71.9 ± 12.9
74.1 ± 8.4
67.8 ± 8.6
Serum protein
[61–79 g/L]
45
66.0 ± 6.4
65.9 ± 6.6
65.8 ± 6.4
66.4 ± 6.8
Serum albumin
[35–48 g/L]
64
38.26 ± 4.51
40.5 ± 4.5°
37.3 ± 3.6
38.1 ± 4.7
Serum osteocalcin
[8.8–29.7 μg/L]
44
20.49 ± 11.30
19.2 ± 11.2
19.3 ± 9.0
28.4 ± 14.1
Serum total alkaline phosphatase
[30–125 IU/L]
61
46 (18)
48 (21)
41 (10)*
51 (14)
Serum IGF-I
[116–447 ng/mL]
66
118 (86)
103 (81)
129 (81)
144 (133)
Serum IGFBP-3
[3.3–6.7 µg/mL]
34
4.63 ± 1.21
4.4 ± 1.3
4.9 ± 1.0
4.9 ± 1.2
Serum parathyroid hormone
[1.1–6.8 pmol/L]
58
3.1 (1.5)
3.0 (1.4)
3.0 (1.8)
3.7 (1.3)
25-hydroxyvitamin D
[25–120 nmol/L]
57
74 (43)
69 (36)
76 (66)
73 (65)
Urinary calcium/creatinine
[0.10–0.50 mmol/mmol]
59
0.37 (0.44)
0.6 (0.6)°
0.3 (0.3)
0.2 (0.3)
Urinary D-pyr/cr2
[4.2–18.2 nmol/mmol]
52
17.7 (10.1)
18.1 (7.0)
13.4 (11.0)
16.0 (10.1)
TRCaI/GFR3
[2.4–2.9 mmol/L GFR]
55
2.59 ± 0 .21
2.54 ± 0.2
2.64 ± 0.2
2.67 ± 0.2
TmPi/GFR4
[0.8–1.4 mmol/L GFR]
55
1.4 (0.3)
1.4 (0.3)
1.3 (0.3)
1.5 (0.5)
Age-adjusted normal values were taken into account.
1At the time of evaluation, and including 3 patients taking oral contraceptives, but continuing to be amenorrheic.
2Deoxypyridinoline/creatinine.
3Renal tubular reabsorption of calcium index.
4Renal tubular reabsorption of phosphate. versus current estrogen use and eugonadal women.
current estrogen versus eugonadal women.