Clinical Study

Recombinant Human Leptin Does Not Alter Gut Hormone Levels after Gastric Bypass but May Attenuate Sweet Cravings

Table 3

Visual analog scale.

PlaceboLeptin
Week 0Week 16Week 0Week 16

How hungry are you?2460 ± 4793761 ± 5692747 ± 5243200 ± 592
How satisfied are you?7606 ± 8196537 ± 9245283 ± 8854719 ± 969
How full do you feel?7428 ± 7856241 ± 8905286 ± 8485197 ± 933
How much do you crave something sweet?2120 ± 5172898 ± 563*2391 ± 5431461 ± 585*
How much can you eat now?3221 ± 4544264 ± 5293453 ± 4923246 ± 557
How much nausea or discomfort do you feel?2958 ± 5082330 ± 5773056 ± 5492888 ± 604

Values represent mean ± SEM AUC from fasting to 120 min after consumption of the test meal. for within-group change.