Research Article

Differences in the Cardiometabolic Control in Type 2 Diabetes according to Gender and the Presence of Cardiovascular Disease: Results from the eControl Study

Table 1

Demographic, clinical characteristics, and degree of cardiometabolic control by gender and presence of .

All patientsCVDNo CVD
MenWomenMenWomenMenWomen
= 153,987 = 132,804 = 34,283 = 18,382 = 119,704 = 114,422

CV risk factors
 Age, mean (SD), years66.4 (11.3)70.3 (11.1)70.9 (9.6)75.6 (8.7)65.1 (11.4)69.4 (11.2)
 Diabetes duration, mean (SD), years6.2 (4.8)6.9 (5.3)7.3 (5.5)8.3 (6.4)5.9 (4.5)6.7 (5.1)
 Hypertension, %58.669.769.581.555.467.8
 Systolic BP, mean (SD), mmHg136.9 (13.6)137.5 (14)136.1 (14.3)138 (14.7)137.2 (13.4)137.5 (13.8)
 Diastolic BP, mean (SD), mmHg76.6 (8.5)76.2 (8.1)73.8 (8.4)73.6 (8.2)77.5 (8.3)76.6 (8)
 Diabetic retinopathy, %5.66.18.310.94.85.4
 Diabetic nephropathy, %20.712.326.718.31911.3
 BMI, mean (SD), kg/m228.8 (4.3)30.5 (5.6)28.6 (4.1)30.1 (5.4)28.9 (4.3)30.6 (5.6)
 HbA1c, %7.2 (1.5)7.1 (1.4)7.1 (1.4)7.2 (1.4)7.2 (1.5)7.1 (1.4)
 Total cholesterol, mean (SD), mg/dL186.2 (38.2)198.4 (38)171.5 (36.9)185.6 (39.4)190.5 (37.5)200.4 (37.3)
 HDL-cholesterol, mean (SD), mg/dL46.2 (12.3)52.7 (13.4)44.4 (11.8)50.2 (12.9)46.7 (12.4)53.1 (13.4)
 LDL-cholesterol, mean (SD), mg/dL109.7 (32.2)115.6 (32.3)97.1 (30.7)104.4 (32.5)113.6 (31.6)117.4 (31.9)
 Triglycerides, mean (SD), mg/dL158.5 (117.3)153.5 (88.7)153.4 (106.8)156.3 (91.8)160 (120.3)153.1 (88.2)
 Smoking status, %
  Non smokers43.58842.490.143.887.6
  Current smokers23.96.218.13.825.66.6
  Ex-smoker32.65.839.56.130.65.8
Degree of CVRF control
HbA1c ≤ 7%, % 55.856.55554.65656.8
BMI ≤ 30 kg/m2, %6147.362.549.760.646.9
BP ≤ 140/90 mmHg, %63.963.165.562.163.563.2
LDL-cholesterol ≤ 130 mg/dL, % (PP) 75.269.486.380.271.867.7
LDL-cholesterol ≤ 100 mg/dL, % (SP) 41.334.258.849.235.931.7
HbA1c ≤ 7% + BP ≤ 140/90 mmHg + LDL ≤ 130 mg/dL, %28.525.633.128.927.025.1
HbA1c ≤ 7% + BP ≤ 140/90 mmHg + LDL ≤ 100 mg/dL, %15.712.422.817.713.511.5

All variables showed significant differences between sexes () and between CVD and no CVD in both men and women (), except for HbA1c: in men and in women. BMI: body mass index; BP: blood pressure; CVD: cardiovascular disease; PP: primary prevention; SD: standard deviation; SP: secondary prevention.