International Journal of Endocrinology / 2014 / Article / Tab 4

Research Article

Honokiol Protected against Heatstroke-Induced Oxidative Stress and Inflammation in Diabetic Rats

Table 4

The serum levels of blood urea nitrogen (BUN), creatinine (C), alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphate (AP) for (NTDR + V) group, (HSDR + V) group, and (HSDR + H) group.

Treatment groups/timeBUN (mmol/L)C (mmol/L)ALT (U/L)AST (U/L)AP (U/L)

(1) NTDR + V:
 0 min (8) (8) (8) (8) (8)
 60 min (8) (8) (8) (8) (8)
(2) HSDR + V:
 0 min (8) (8) (8) (8) (8)
 60 min (8) (8) (8) (8) (8)
(3) HSDR + H:
 0 min (8) (8) (8) (8) (8)
 60 min (8) (8) (8) (8) (8)

All heatstroke rats which had heat exposure (43°C) were withdrawn exactly at 60 minutes and then allowed to recover at room temperature (26°C). Data are mean ± SD, followed by number of animals in parentheses.
, in comparison with Group 1.
, in comparison with Group 2 (Dunn’s test followed by Kruskal-Wallis test). Vehicle solution (V) or honokiol (H) was adopted 60 min before the start of heat stress.

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