International Journal of Endocrinology / 2014 / Article / Tab 3

Research Article

Impact of NRAS Mutations on the Diagnosis of Follicular Neoplasm of the Thyroid

Table 3

Clinicopathologic features and the NRAS mutation status of 63 benign lesions with a preoperative diagnosis of follicular neoplasm.

Patients with a NRAS negative benign nodule Patients with a NRAS positive benign nodule
-value

Average tumor size (cm)2.2 ± 1.51.4 ± 0.70.010
Age
45 years14 (74%)5 (26%)0.224
 >45 years38 (86%)6 (14%)
Gender
 Female45 (83%)9 (17%)0.684
 Male7 (78%)2 (22%)
Histopathology
 Follicular adenoma 41 (80%)10 (20%)0.355
 Nodular hyperplasia11 (92%)1 (8%)