Effect of Bile Acid on Fetal Lung in Rat Model of Intrahepatic Cholestasis of Pregnancy
The morphology of fetal rat lungs in light microscope. (a) The high bile acid group: immature fetal lung tissue with smaller alveolar space, thicker alveolar septal, and a large number of hemorrhagic lesions were observed. HE: 100 (A1), 400 (A2). (b) The low bile acid group: fetal lung tissue with small alveolar space and thick alveolar septal were observed. HE: 100 (B1), 400 (B2). (c) The experimental control group: mature fetal lung tissue with large alveolar space and thin alveolar septal were observed. Alveolar epithelial cells, cytoplasm stained (red), and nuclear (flat). HE: 100 (C1), 400 (C2).