Research Article

Alterations in the Corneal Nerve and Stem/Progenitor Cells in Diabetes: Preventive Effects of Insulin-Like Growth Factor-1 Treatment

Figure 3

Decreased expression levels of corneal progenitor/stem cell markers in diabetes. Representative immunostained micrographs of the cross-sections of the normal ((a) and (c)) and diabetic ((b) and (d)) corneas showing the expression of stem cell markers. Expression levels of Hes1 (b) and Keratin19 (d) decreased in diabetic eyes after 12 weeks compared with those in the normal eyes ((a) and (c)).
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(a)
312401.fig.003b
(b)
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(c)
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(d)