Research Article

Increased Circulating Betatrophin Concentrations in Patients with Type 2 Diabetes

Table 2

Correlations between betatrophin levels and other variables in all study participants, nondiabetic controls, and patients with type 2 diabetes. Correlations were computed with Pearson product moment.

Betatrophin correlationsAll study participants
(n = 45)
Nondiabetic
(n = 18)
Type 2 diabetes
(n = 27)

Age (years)Ns, cc = 0.113 * P = 0.01
cc = 0.572
Ns, cc = 0.075
Weight (kg)Ns, cc = 0.0535Ns, cc = −0.236Ns, cc = 0.176
BMI (kg/m2)Ns, cc = 0.0915Ns, cc = −0.164Ns, cc = 0.15
Waist (cm)Ns, cc = 0.111Ns, cc = −0.173Ns, cc = 0.192
Hip (cm)Ns, cc = −0.0740Ns, cc = −0.142Ns, cc = 0.411
Waist-hip ratioNS, cc = −0.243Ns, cc = −0.143Ns, cc = −0.415
Fasting plasma glucose (mmol/L)Ns, cc = 0.235Ns, cc = −0.054Ns, cc = 0.082
HbA1c (% (mmol/mol)) * P = 0.0005
cc = 0.495
Ns, cc = −0.060 * P = 0.01
cc = 0.482
HOMA2%BNs, cc = −0.0502Ns, cc = 0.28Ns, cc = 0.0389
HOMA2%SNs, cc = 0.0685Ns, cc = −0.13Ns, cc = 0.119
HOMA2 IRNs, cc = 0.190Ns, cc = 0.18Ns, cc = 0.109
Fasting plasma cholesterol (mmol/L)Ns, cc = −0.286Ns, cc = −0.21Ns, cc = −0.06
Fasting plasma HDL cholesterol mmol/LNs, cc = −0.0835Ns, cc = 0.18Ns, cc = −0.022
Fasting plasma LDL cholesterol mmol/LNs, cc = −0.230Ns, cc = −0.33Ns, cc = 0.087
Fasting plasma triacylglycerols (mmol/L)Ns, cc = −0.178Ns, cc = −0.27Ns, cc = −0.12
Plasma creatinine (µmol/L)Ns (P = 0.0579), cc = 0.267Ns, cc = −0.045Ns, cc = 0.342
GFR-MDRD (mL/min)Ns (P = 0.17), cc = −0.208Ns, cc = −0.169Ns, cc = −0.209
Fasting plasma C-peptide (nmol/L)Ns, cc = 0.168Ns, cc = 0.195Ns, cc = 0.103

P < 0.05, Ns: not significant (P > 0.05), and cc: correlation coefficient, also known as r.