Fasting Leptin Is a Metabolic Determinant of Food Reward in Overweight and Obese Individuals during Chronic Aerobic Exercise Training
Table 1
Body composition and metabolic values during the 12-week exercise intervention ().
Baseline
Week six
Postintervention
Delta Δ
value
Body mass (kg)
88.21 (2.04)
87.39 (2.00)
86.49 (2.04)
−1.72 (0.41)
0.000*
Fat mass (kg)
35.71 (1.34)
34.48 (1.35)
33.49 (1.43)
−2.23 (0.38)
0.000*
Fat mass index (kg/m2)
12.61 (0.52)
12.17 (0.53)
11.85 (0.56)
−0.76 (0.14)
0.000*
Body fat (%)
40.33 (1.13)
39.24 (1.16)
38.43 (1.22)
−1.90 (0.32)
0.000*
Fat-free mass (kg)
52.48 (1.43)
52.91 (1.41)
53.00 (1.39)
0.52 (0.17)
0.081
Fat-free mass index (kg/m2)
18.25 (0.31)
18.40 (0.30)
18.41 (0.30)
0.17 (0.62)
0.009*
VO2peak (mL·kg−1·min−1)
33.33 (1.17)
37.45 (1.08)
39.16 (0.09)
5.83 (0.95)
0.000*
Fasting glucose (mmol·L−1)
4.93 (0.15)
4.88 (0.17)
4.73 (0.19)
−0.20 (0.25)
0.415
Fasting insulin (ng·L−1)
1034.32 (106.24)
918.77 (105.33)
991.34 (113.24)
−42.98 (82.94)
0.230
HOMA index
3.18 (0.31)
2.92 (0.31)
3.02 (0.33)
−0.16 (0.25)
0.554
Fasting leptin (ng·L−1)
38318.80 (4832.26)
369923.92 (4612.41)
32102.87 (5333.58)
−6215.93 (3076.37)
0.023*
Delta Δ: baseline to postintervention change. VO2peak: maximal aerobic capacity. HOMA: homeostatic model of assessment. *Significant difference between baseline and postintervention ().
