Research Article

Functional Analysis of Thyroid Peroxidase Gene Mutations Detected in Patients with Thyroid Dyshormonogenesis

Table 3

Clinical manifestations of case at initial presentation.

Clinical manifestations Case ( ) % Control ( ) % value

*Family history
 Present 9346.563<0.0001
 Absent 10753.519497
*Goiter
 Present13165.5
*Weight gain
 Yes904567340.024
 No1105513366
Loss of memory
 Yes1025190450.27
 No 984911055
*Lethargy
 Yes12261 91460.002
 No 783910954
*Muscle cramp
 Yes11055 88440.03
 No904511256
*Cold intolerance
 Yes12060113570.54
 No 80 408743
*Constipation
 Yes10955 80400.005
 No914512060

at the time of diagnosis.