Research Article

Pretransplant HbA1c Is a Useful Predictor for the Development of New-Onset Diabetes in Renal Transplant Recipients Receiving No or Low-Dose Erythropoietin

Table 1

Comparison of patients who developed NODATa (NODAT+) to those who did not (NODAT−).

VariableNODAT+
( = 17)
NODAT−
( = 102)
value

Recipient age [y]47.5 (10.5)38.7 (11.7)<0.005
Recipient gender (M/F)(15/2)(64/38)0.05
Donor age [y]53.4 (7.9)55.6 (10.2)0.38
Donor gender (M/F)(4/13)(36/66)0.42
Fasting plasma glucose [mg/dL]82.9 (6.9)80.1 (9.0)0.22
HbA1c [%]5.2 (0.45)4.9 (0.45)<0.05
Hemoglobin [g/L]10.6 (2.4)10.4 (1.8)0.60
EPOb (none/low-dosec/high-dosed)(1/11/4)(15/59/25)0.74
Cause of chronic renal failure0.50
 Glomerulonephritis13 (76%)62 (61%)
 Polycystic kidney disease0 (0%)4 (4%)
 Hypertension/nephrosclerosis1 (6%)4 (4%)
 Other/unknown3 (18%)32 (31%)
Pretransplant BMIe21.1 (2.6)21.2 (3.1)0.95
Dialysis period [mo]24 (0–171)15 (0–198)0.23
Hepatitis C positive2 (12%)1 (1%)0.05
ABO incompatible3 (18%)15 (15%)0.72

aNew-onset diabetes after transplantation.
bErythropoietin.
c0 < EPO ≤ 6,000 IU/week.
dEPO > 6,000 IU/week.
eBody mass index [kg/m2].