High Risk First Degree Relatives of Type 1 Diabetics: An Association with Increases in CXCR3⁺ T Memory Cells Reflecting an Enhanced Activity of Th1 Autoimmune Response

Table 1

Characteristics of first degree relatives of patients with T1D (FDRs) at high risk (hr FDRs) and low risk (lr FDRs) for development of T1D, patients with recent-onset T1D (R-T1D) in insulin-requiring state (IRS), and healthy controls (HC) included in CD4⁺ T cells analysis in the peripheral blood.

Group	Number	Gender (m/f)	Age (years)	BMI (kg/m^2)
hr FDRs	17	4/13	29.82 ± 8.83	23.71 ± 2.66
lr FDRs	34	18/16	26.44 ± 6.09	22.69 ± 3.72
RT1D-IRS	24	15/9	26.43 ± 6.02	21.40 ± 3.47
HC	18	2/16	28.18 ± 7.21	22.00 ± 4.21