Markers of Systemic Inflammation and Apo-AI Containing HDL Subpopulations in Women with and without Diabetes
Table 1
Lipid profile, Apo-AI containing HDL subpopulations distribution, and markers of systemic inflammation in women with and without type 2 diabetes.
Total population
Women with type 2 diabetes
Women without type 2 diabetes
160
80
80
Postmenopausal ()
86
43
43
Age (yrs)
—
Menopausal duration (yrs)
—
BMI (Kg/m2)
<0.001
Waist circumference (cm)
<0.001
Systolic BP (mmHg)*
<0.001
Diastolic BP (mmHg)
<0.001
Fasting BG (mg/dL)*
<0.001
Lipid and lipoprotein profile
Total-C (mg/dL)#
—
LDL-C (mg/dL)#
—
Triglycerides (mg/dL)
0.001
HDL-C (m/dL)*
<0.0001
Apo-AI (mg/dL)#
0.04
Apo-AII (mg/dL)
0.01
Apo-AI containing HDL subpopulations profile
α-1 HDL (mg/dL)
0.006
α-2 HDL (mg/dL)
0.005
α-3 HDL (mg/dL)
0.02
Pre-α-1 (mg/dL)
0.025
Markers of systemic inflammation
hsCRP (mg/L)*
0.001
IL-6 (pg/mL)*
—
Data are , means ± SD. Only significant values for the comparisons between diabetic and nondiabetic women are presented. Total-C: total cholesterol; Apo: apolipoprotein. *Age- and BMI-adjusted value < 0.001; age- and BMI-adjusted value < 0.05; #nonsignificant age- and BMI-adjusted value.
