Dynamic Interactive Educational Diabetes Simulations Using the World Wide Web: An Experience of More Than 15 Years with AIDA Online
Figure 5
(a) AIDA online2 simulation of the case shown in Figure 4(c) in which the evening (7:30 pm) Actrapid dose has been increased by 2 units from 4 units to 6 units. The current simulation run is shown as the vertical red lines, with the previous run shown for comparison as the solid blue lines. The higher plasma insulin peak in the evening and the reduction in blood glucose (BG) overnight are clear to see, although the BG profile still remains elevated compared with the user defined normoglycaemic range. The glycosylated haemoglobin () level—if this control were maintained in the medium-to-long-term—is expected to improve from 8.6% (Figure 4(c)) to 8.3%. (b) AIDA online2 simulation of the case shown in (a) in which the evening (11 pm) Ultralente dose has been increased by 2 units from 8 units to 10 units, resulting in some further improvement in the blood glucose (BG) profile, with an expected glycosylated haemoglobin () of 7.9% (improved from 8.3% in (a)). The current simulation run is shown as the vertical red lines, with the previous run shown for comparison as the solid blue lines. (c) AIDA online2 simulation of the case shown in (b) in which the bedtime snack has been decreased by 5 grams from 10 grams to 5 grams and supper has been decreased by 10 grams from 40 grams to 30 grams (in one simulation). This results in further improvement in the simulated blood glucose profile with a predicted glycosylated haemoglobin () of 7.6%. Once again, the current simulation run is shown as the vertical red lines, with the previous run shown for comparison as the solid blue lines.
