Effects of Maternal Hypoxia during Pregnancy on Bone Development in Offspring: A Guinea Pig Model
Figure 1
Effects of MH on total thickness and zonal heights in the growth plate of offspring. H&E-stained tibial sections (showing growth plate height) of 120d postnatal guinea pigs from a control (a) and a hypoxic (b) mother, respectively. The dashed lines in (a) and (b) arbitrarily separate the three individual growth plate zones. (c) Total growth plate thickness and zonal heights (resting, black bar; proliferative, grey bar; hypertrophic, white bar) of 62d gestation fetal guinea pigs from control and hypoxia-treated mothers. (d) Total growth plate thickness and zonal heights of 120d postnatal guinea pigs from control and hypoxia-treated mothers (). Scale bar in (a) = 250 μm and applies to (b).
