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International Journal of Endocrinology
Volume 2014 (2014), Article ID 921934, 6 pages
http://dx.doi.org/10.1155/2014/921934
Research Article

Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease

1Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 110-746, Republic of Korea
2Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan 614-734, Republic of Korea

Received 23 June 2014; Revised 24 November 2014; Accepted 25 November 2014; Published 8 December 2014

Academic Editor: Jack R. Wall

Copyright © 2014 Myung Ho Rho and Dong Wook Kim. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. This study aimed to evaluate the CT features of incidentally detected DTD in the patients who underwent thyroidectomy and to assess the diagnostic accuracy of CT diagnosis. Methods. We enrolled 209 consecutive patients who received preoperative neck CT and subsequent thyroid surgery. Neck CT in each case was retrospectively investigated by a single radiologist. We evaluated the diagnostic accuracy of individual CT features and the cut-off CT criteria for detecting DTD by comparing the CT features with histopathological results. Results. Histopathological examination of the 209 cases revealed normal thyroid (), Hashimoto thyroiditis (), non-Hashimoto lymphocytic thyroiditis (), and diffuse hyperplasia (). The CT features suggestive of DTD included low attenuation, inhomogeneous attenuation, increased glandular size, lobulated margin, and inhomogeneous enhancement. ROC curve analysis revealed that CT diagnosis of DTD based on the CT classification of “3 or more” abnormal CT features was superior. When the “3 or more” CT classification was selected, the sensitivity, specificity, positive and negative predictive values, and accuracy of CT diagnosis for DTD were 55.8%, 95.5%, 80.6%, 86.7%, and 85.6%, respectively. Conclusion. Neck CT may be helpful for the detection of incidental DTD.