Augmented β-Cell Function and Mass in Glucocorticoid-Treated Rodents Are Associated with Increased Islet Ir-β/AKT/mTOR and Decreased AMPK/ACC and AS160 Signaling

Table 2

Metabolic variables in 12 hour fasting DEX-treated mice and rats.

	Mice		Rats
	CTL	DEX	CTL	DEX
Cholesterol (mg/dL)	169.7 ± 14.2	302.0 ± 18.3*	23.8 ± 1.8	30.6 ± 1.7*
Triacylglycerol (mg/dL)	106.9 ± 12.4	201.0 ± 13.8*	111.2 ± 14.2	210.1 ± 26.6*
NEFA (mMol/L)	1.2 ± 0.09	1.1 ± 0.08	0.6 ± 0.04	0.9 ± 0.09*
Glycemia (mMol/L)	5.5 ± 0.3	5.0 ± 0.4	5.5 ± 0.08	8.8 ± 0.8*
Insulinemia (pMol/L)	31.9 ± 3.09	59.9 ± 9.6*	268.6 ± 64.3	2697.4 ± 439.0*

Significantly different using unpaired -test versus CTL ; = 8–10; values are mean ± s.e.m.