Urinary Angiopoietin-2 Is Associated with Albuminuria in Patients with Type 2 Diabetes Mellitus

Table 1

Clinical and laboratory characteristics.

Group	NC	DN1	DN2	DN3
Number	30	38	37	38	—
Age (year)					>0.05
Male/female	17/13	23/15	20/17	21/17	>0.05
BMI (kg/m^2)					>0.05
SBP (mmHg)					<0.001^*
DBP (mmHg)					>0.05
Total cholesterol (mmol/L)					>0.05
LDL-ch (mmol/L)					>0.05
TG (mmol/L)					>0.05
HDL-ch (mmol/L)					>0.05
UAER (μg/min)	0				<0.001^*
24 h UPQM (g/24 h)	0				<0.001^*
Serum Cr (μmol/L)					<0.001^*
GFR (mL/min)					<0.001^*
HbA1c (%)					<0.001^*
FBS (mmol/L)					<0.001^*

Data are expressed as mean ± standard error of the mean (SEM). values were estimated using analysis of variance (ANOVA) or the Kruskal-Wallis test.
NC: normal control; DN1: normal-albuminuria group; DN2: microalbuminuria group; DN3: macroalbuminuria; BMI: body mass index; Cr: creatinine; DBP: diastolic blood pressure; GFR: glomerular filtration rate; FBS: fasting blood sugar; HDL-ch: high-density lipoprotein cholesterol; LDL-ch: low-density lipoprotein cholesterol; SBP: systolic blood pressure; TG: triglyceride; UAER: urinary albumin excretion rate; 24 h UPQM: 24 h urinary protein quantitative measurements; HbA1c: glycosylated hemoglobin; ^*significant difference between diabetic patients and controls.