Polymorphism in LEP and LEPR May Modify Leptin Levels and Represent Risk Factors for Thyroid Cancer

Table 3

Mean and median leptin serum expressions according to the genotypes of the studied SNPs.

Gene-rs ()	Mean; expression; (ng/mL)	Standard deviation	Median (ng/mL)
LEP rs7799039 (78)				0.012^*
AA (12)	9.22	0.98	9.37	<0.05^#
AG (36)	10.07	0.60	10.07	>0.05^$
GG (30)	9.75	0.56	9.84	>0.05^$
LEP rs2167270 (78)				0.018^*
AA (8)	9.89	0.49	9.80	>0.05^#
AG (38)	10.05	0.59	10.00	<0.05^&
GG (32)	9.52	0.79	9.58	>0.05^$
LEPR rs1137101 (78)				N.S.
AA (20)	9.75	0.59	9.83
AG (40)	9.89	0.76	9.85
GG (18)	9.74	0.74	9.96
LEPR rs1137100 (73)				N.S.
AA (48)	9.88	0.76	9.96
AG (20)	9.77	0.72	9.84
GG (5)	9.76	0.42	9.86

AA × AG × GG; ^#AA × AG; ^&AG × GG; AA × GG; N.S.: nonsignificant.