The Effect of Long-Term Intranasal Serotonin Treatment on Metabolic Parameters and Hormonal Signaling in Rats with High-Fat Diet/Low-Dose Streptozotocin-Induced Type 2 Diabetes

Figure 2

The concentration of plasma glucose in the glucose tolerance test in diabetic and nondiabetic rats on the 60th (a), 90th (b), and 147th days (c) and the concentration of insulin in glucose tolerance test on the 147th day (d) of experiment. In Figures 2(a) and 2(b): Group C () and Group D (). In Figures 2(c) and 2(d): Group C (), Group ND + SER (), Group D0 (), and Group D + SER (). The data are presented as M SD. (, ) The difference between Groups C and D (a, b) and between Groups C0 and D0 (c) and (#, ##) the difference between Groups C0 and ND + SER (1) or between Groups D0 and D + SER (2) are significant at and , respectively.

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