Clinical Study

Evaluating the Efficacy of Treatment with a GnRH Analogue in Patients with Central Precocious Puberty

Table 3

Characteristics of patients without HPG axis suppression (mean ± SD) (range).

Treatment durationChronological age
(years)
BMI
SDS
Stage of puberty
(median) (range)
Basal LH (mIU/mL)Peak LH (mIU/mL)E2 (pg/mL)

Pretreatment ()8.6 ± 1.0
(7.0–10.1)
0.9 ± 0.8
(0.7–2.2)
3 (2–4)2.2 ± 3.3 (0.1–10.3)11.1 ± 10.6 (5.6–27.1)32.9 ± 24.0 (7.0–68.3)
3rd month ()8.9 ± 1.0
(7.3–10.4)
0.8 ± 0.7
(0.7–2.0)
3 (1–4)0.1 ± 0.0 (0.1–0.2)4.7 ± 1.9 (3.0–8.4)13.7 ± 6.9 (7.0–22.6)
6th month ()9.5 ± 1.2
(7.5–10.5)
0.9 ± 0.6
(0.8–2.1)
3 (2–4)0.4 ± 0.1 (0.2–0.6)4.8 ± 0.8 (3.8–6.0)14.1 ± 9.8 (7.0–30.8)
9th month ()9.7 ± 1.6
(7.8–10.8)
0.9 ± 1.0
(0.8–2.2)
3 (2–4)0.4 ± 0.1 (0.4–0.6)3.8 ± 0.3 (3.6–4.2)18.6 ± 7.6 (11.8–26.8)

BMI: body mass index; SDS: standard deviation score.