Cushing’s Disease: The Relevance of a Combined Dexamethasone Desmopressin Test as a Component of Postoperative Hormonal Evaluation

Table 4

Relative (Δ%) changes in cortisol and ACTH levels at consecutive time points versus baseline, stratified by remission status.

	Remission ()			Persistent CD ()			value
	Mean ± SD	Median	Range	Mean ± SD	Median	Range
Cortisol (μg/dL)
15′	32.0 ± 99.6	0.0	−2.2–389.5	185.0 ± 180.8	119.1	1.9–514.8	<0.001
30′	35.0 ± 106.6	7.9	−16.7–417.5	265.6 ± 253.7	175.2	9.7–854.9	<0.001
60′	23.3 ± 70.6	0.0	−14.2–274.1	290.3 ± 274.6	191.3	11.0–912.3	<0.001
90′	17.9 ± 47.3	0.0	−15.8–179.7	262.5 ± 261.8	151.9	−5.3–723.8	<0.001
120′	9.7 ± 37.6	0.0	−10.8–144.8	223.3 ± 249.9	124.0	−17.4–788.6	<0.001
ACTH (pg/mL)
15′	143.4 ± 129.9	100.0	0.0–433.3	539.1 ± 882.0	177.8	5.3–2602.4	0.121
30′	91.0 ± 103.7	46.7	−25.0–300.0	461.7 ± 673.2	157.9	15.8–2042.9	0.024
60′	27.5 ± 61.2	26.7	−50.0–166.7	231.8 ± 317.0	91.7	5.3–1095.2	0.004
90′	11.4 ± 54.9	0.0	−63.6–133.3	156.1 ± 256.7	53.1	10.5–950.0	0.004
120′	1.5 ± 42.6	0.0	−50.0–100.0	119.0 ± 241.7	10.5	−22.2–840.5	0.011