Research Article
Effect of Orexin-A on Cortisol Secretion in H295R Cells via p70S6K/4EBP1 Signaling Pathway
Figure 1
Orexin-A stimulates the p70S6K activity in H295R cells. Cells were stimulated with orexin-A (10−6 M) for the indicated time periods (a) or orexin-A (10−9 M–10−6 M) for 1 h (b). The expressions of p70S6K protein were measured via western blot analysis. Data are presented as mean ± SEM based on three independent experiments. Asterisk indicates significant differences as compared to control ().
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