The Warthin-Like Variant of Papillary Thyroid Carcinoma: A Comparison with Classic Type in the Patients with Coexisting Hashimoto’s Thyroiditis

Table 2

Comparison of clinicopathologic characteristics between classic PTC with or without HT.

Characteristic	Classic PTC with HT ()	Classic PTC without HT ()	value
Median age (years)	46 (25–73)	45 (22–73)	0.357
Age			0.261
<45	21 (40%)	73 (50%)
≥45	32 (60%)	74 (50%)
Sex			<0.001
Female	52 (98%)	109 (74%)
Male	1 (2%)	38 (26%)
Multifocality			0.264
Single	25 (47%)	83 (57%)
Multiple	28 (53%)	64 (44%)
Surgery type			0.122
Lobectomy	12 (23%)	51 (35%)
Total thyroidectomy	41 (77%)	96 (65%)
Median tumor size (cm)	0.7 (0.3–4.5)	0.6 (0.2–3.3)	0.343
pT stage			0.532
pT1	34 (64%)	89 (61%)
pT2	1 (2%)	1 (1%)
pT3	18 (34%)	57 (39%)
Extrathyroidal extension			0.620
Absent	35 (66%)	90 (61%)
Present	18 (34%)	57 (39%)
pN stage			0.262
pN0	31 (59%)	71 (48%)
pN1	22 (42%)	76 (52%)
Preoperative diagnosis			0.904
Atypia of undetermined significance	2 (4%)	5 (3%)
Suspicious for PTC	13 (25%)	32 (22%)
PTC	38 (72%)	110 (75%)
BRAF mutation			0.031
Absent	14 (26%)	19 (13%)
Present	39 (74%)	128 (87%)

PTC, papillary thyroid carcinoma; WLPTC, Warthin-like variant of papillary thyroid carcinoma; HT, Hashimoto’s thyroiditis.