Clinical Study

Sex, Prescribing Practices and Guideline Recommended, Blood Pressure, and LDL Cholesterol Targets at Baseline in the BARI 2D Trial

Table 4

Achievement of clinical targets for HbA1c, blood pressure, and LDL-cholesterol at baseline in BARI 2D by sex.

Clinical target% at clinical targetOdds ratio (95% CI)
Female 
()
Male 
()
valueUnadjusted female versus maleAdjusted female versus male

HbA1c < 7%31.9%42.3%<0.0010.64 (0.53, 0.77)0.71 (0.57, 0.88)
Blood pressure ≤ 130/80 mm Hg45.0%48.6%0.120.87 (0.72, 1.04)1.11 (0.92, 1.35)
LDL < 100 mg/dL49.8%63.1%<0.0010.58 (0.48, 0.69)0.64 (0.53, 0.78)
Achieved all 3 target goals10.9%15.8%0.0020.65 (0.49, 0.86)0.78 (0.58, 1.04)

All clinical targets were adjusted for the following common covariates: sex, age, race ethnicity, education, physical activity, cigarette smoking, duration of diabetes, and BMI. In addition, HbA1c was adjusted for a number of diabetes agents; lipids targets were adjusted for a number of lipids agents and CABG or PCI prior to randomization; blood pressure target was adjusted for a number of antihypertensive agents, CABG or PCI prior to randomization, and history of hypertension. The attainment on all 3 targets was controlled for a number of total drugs, CABG or PCI prior to randomization, and history of hypertension.