Retrospective review of a prospectively collected pediatric neurotrauma registry
Children admitted with severe TBI (GCS ≤8). Mean age of 81 months ().
Mean glucose concentrations in the early period (<48 hours) were similar in children with favorable and unfavorable outcomes. Hyperglycemia in the late period (49–168 hours) was associated with unfavorable GOS at 6 months.
As part of the protocol, if serum glucose ≥70 mg/dL, glucose administration was avoided for 48 hours after TBI.
Children admitted with GCS of 3–10, between 24 months and 12 years. Mean age of (of cases) 7 years (, 37 controls).
The hyperglycemic response was more common among those with head trauma (40% compared to controls (5%) but within the head trauma group, the level of hyperglycemia was not associated with death or need for extended care).
GCS on admission was a significant prognostic indicator. In this study, authors conclude that the hyperglycemia is transient and does not warrant treatment with insulin.
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