Research Article

Role of Paricalcitol in Modulating the Immune Response in Patients with Renal Disease

Table 3

Univariate and multiple regression analysis of NGAL in CKD patients.
(a) In vivo

VariablePartial β value

ESR0.35 (p  )0.320.001
hs-CRP0.81 (p  )0.81<0.0001
IL-170.64 (p  )0.320.006
IL-60.90 (p  )0.78<0.0001
IFN-γ0.90 (p  )0.75<0.0001
TNF-α0.59 (p  )0.76<0.0001
IL-1β0.51 (p  )0.230.13

(b) In vitro

VariablePartial β value

ESR0.35 (p  )0.750.4
hs-CRP0.36 (p  )0.350.3
IL-170.97 (p  )0.410.07
IL-6 0.94 (p  )0.590.0001
TNF-α0.96 (p  )0.430.0002
IL-1β0.97 (p  )0.080.001
Vitamin D0.48 (p  )−0.280.001

Dependent variable: NGAL; β: standardized coefficient of correlation.
NGAL: neutrophil gelatinase associated lipocalin; IL-17: interleukin-17; IL-6: interleukin-6; IL-1β: interleukin-1 beta; IFN-γ: interferon-gamma; TNF-α: tumor necrosis factor-alpha; hsCRP: high-sensitivity C-reactive protein; ESR: erythrocyte sedimentation rate.