Association of Pre-miR-146a rs2910164 Polymorphism with Papillary Thyroid Cancer

Table 1

Characteristics of the study subjects.

Variables	Cases ()	Controls ()
Age	43.43 ± 9.204	43.38 ± 9.311	−0.123	0.902
Gender
Male	321 (25.9)	339 (26.6)	0.132	0.716
Female	916 (74.1)	936 (73.4)
History of thyroid disease
Yes	114 (9.4)
No	1093 (90.6)
Family history
Yes	160 (13.6)
No	1017 (86.4)
Smoking
Nonsmokers	1066 (88.8)
Smokers	119 (9.9)
Ex-smokers	15 (1.2)
Stage
0-I	597 (81.7)
II	36 (4.9)
III	35 (4.8)
IV	63 (8.6)
Metastasis (pN+)
Yes	399 (33.6)
No	788 (66.4)
Location
Unilateral	787 (70.5)
Bilateral	311 (27.9)
Isthmus	18 (1.6)
Diameter
≤1 cm	598 (50.9)
>1 cm	578 (49.1)
Benign tumor
Yes	625 (51.5)
No	588 (48.5)
PTC/benign
Same side	176 (29.3)
Opposite sides	425 (70.7)
Thyroiditis
Yes	106 (8.7)
No	1107 (91.3)