The Blocking on the Cathepsin B and Fibronectin Accumulation in Kidney Glomeruli of Diabetic Rats
Table 2
The values of blood pressure and biochemical parameters evaluated inurine collection.
Groups
Blood pressure
Creatinine clearance
Albuminuria/creatinine
Fibronectin/creatinine
Cathepsin B/creatinine
mm Hg
μL/min/mc
μg/mg
ng/mg
mIU/mg
DM
Mean ± SD
173.36 ± 26.7
2.83 ± 1.16
66.5 ± 44.9
46.73 ± 31.59
0.87 ± 0.27
Median (range)
165.00 (145.00–227.00)
2.68 (1.52–4.63)
39.3 (23.4–133.3)
31.94 (25.04–109.59)
0.81 (0.57–1.38)
EN
Mean ± SD
160.50 ± 26.80
2.9 ± 0.80
40.3 ± 17.5
37.05 ± 11.88
0.81 ± 0.24
Median (range)
164.25 (122.00–202.00)
3.07 (1.57–3.94)
34.3 (20.7–70.3)
32.09 (24.77–61.43)
0.71 (0.58–1.32)
LOS
Mean ± SD
164.90 ± 18.64
3.29 ± 0.85
46.1 ± 24.0
30.77 ± 8.29
0.75 ± 0.35
Median (range)
166.50 (135.00–192.00)
3.02 (2.37–4.46)
44.4 (13.2–98.2)
28.72 (18.82–44.97)
0.64 (0.41–1.48)
EN + LOS
Mean ± SD
160.15 ± 21.81
3.98 ± 0.97
49.2 ± 29.6
29.45 ± 18.28
0.66 ± 0.25
Median (range)
164.50 (110.50–180.00)
4.26 (2.11–5.31)
35.8 (24.9–111.1)
24.00 (15.17–81.20)
0.56 (0.29–1.11)
SPIR
Mean ± SD
168.95 ± 32.76
3.07 ± 0.73
41.2 ± 15.2
36.12 ± 7.67
0.71 ± 0.22
Median (range)
159.50 (120.00–222.00)
3.04 (1.52–4.07)
37.4 (17.6–74.1)
32.50 (29.70–49.70)
0.66 (0.40–1.04)
DIH
Mean ± SD
159.00 ± 15.67
2.9 ± 0.39
39.3 ± 19.8
37.57 ± 12.84
0.73 ± 0.29
Median (range)
159.75 (139.00–190.50)
2.82 (2.46–3.53)
32.8 (16.9–72.1)
37.06 (20.67–58.45)
0.70 (0.21–1.21)
ANOVA test
NS
NS
NS
NS
The results are presented as mean ± SD and median (range). Statistically significant differences between the groups have been shown, the levels of significance in the 95% confidence interval.
Statistical significance with the DM group.
