Gremlin, a Bone Morphogenetic Protein Antagonist, Is a Crucial Angiogenic Factor in Pituitary Adenoma

Figure 1

Merged double immunofluorescence image. Expression of Gremlin and CD34 in pituitary adenoma tissue in a representative case of a 33-year-old male with GHoma, Knosp grade 3; 40x magnification. Yellowish fluorescence indicates colocalization of Gremlin and CD34 in cytoplasma of tumor parenchymal cells (Gremlin, FITC; CD34, PI).