Gender-Specific Effect of -102G>A Polymorphism in Insulin Induced Gene 2 on Obesity in Chinese Children
Table 3
Associations of the -102G>A polymorphism with obesity-related phenotypes in girls and boys.
Total
Boys
Girls
SE
P value
SE
P value
SE
P value
Body mass index (BMI)
0.39
0.33
0.233
0.73
0.45
0.108
0.003
0.47
0.996
BMI-SDS
0.11
0.09
0.207
0.16
0.12
0.173
0.05
0.13
0.687
Waist circumference (cm)
1.11
0.85
0.195
2.61
1.21
0.031
–0.74
1.17
0.527
Hip circumference (cm)
0.76
0.67
0.256
1.65
0.91
0.072
–0.44
0.96
0.649
Waist-hip ratio (WHR)
0.005
0.005
0.346
0.01
0.01
0.073
–0.004
0.01
0.590
Total cholesterol (mmol/L)
0.02
0.06
0.767
0.05
0.08
0.517
–0.03
0.09
0.771
Triglyceride (mmol/L)
0.07
0.04
0.112
0.07
0.06
0.212
0.06
0.06
0.336
Low-density lipoprotein cholesterol (mmol/L)
0.05
0.06
0.428
0.07
0.08
0.355
0.01
0.08
0.897
High-density lipoprotein cholesterol (mmol/L)
0.02
0.02
0.292
0.01
0.03
0.766
0.03
0.03
0.339
Body fat percentage (%)
0.39
0.77
0.617
1.56
1.20
0.196
–0.64
0.96
0.505
Triceps skinfold (mm)
–0.13
0.63
0.839
0.40
0.94
0.672
–0.86
0.82
0.296
Subscapular skinfold (mm)
0.72
0.72
0.313
1.65
1.06
0.121
–0.37
0.94
0.691
Abdominal skinfold (mm)
0.64
0.76
0.404
1.67
1.15
0.148
–0.61
0.95
0.518
Suprailiac skinfold (mm)
0.39
0.70
0.577
1.06
1.06
0.315
–0.53
0.86
0.541
Sum of skinfolds (mm)
1.62
2.63
0.539
4.78
3.95
0.226
–2.37
3.33
0.476
Multiple linear regression was performed under dominant model adjusted for sex, age, age square, and study population in total, while analyses in boys or girls were adjusted for age, age square, and study population. β: unstandardized regression coefficients; SE: standard error.
