Bone Regulates Glucose Metabolism as an Endocrine Organ through Osteocalcin

Table 1

Metabolic phenotypes of ESP and Ocn knocked out mice.

	ESP mice	Ocn mice
Blood glucose	Decreased	Increased
Glucose tolerant	Increased	Decreased
Sensitive to insulin	Increased	Decreased
Beta cells proliferation	Increased	Decreased
ucOCN	Decreased	Absent