Research Article

Thyroid-Specific Genes Expression Uncovered Age-Related Differences in Pediatric Thyroid Carcinomas

Table 1

Summary of the clinicopathological features of pediatric thyroid carcinoma.

Total Patients <10 yr oldPatients ≥10–18 yr old value

Mean age ± SD11.84 (±4.4)6.76 (±1.92)14.48 (±2.63)<0.0001
Gender
 Female 298 (62%)21 (84%)0.2262
 Male95 (38%)3 (16%)
Tumor size (cm) mean ± SD2.65 (±1.48)2.28 (±1.49)2.83 (±1.48)0.2383
Risk factors
 Family history21 (8%)1 (4%)1.00
 Exposure to radiation404 (16%)0.2779
Extrathyroidal extension169 (69%)7 (28%)0.0448
Multifocal disease174 (31%)13 (52%)0.3068
LN metastases2811 (85%)17 (68%)0.4413
Distant metastases106 (46%)4 (16%)0.0620