Polymorphisms of Vitamin D Signaling Pathway Genes and Calcium-Sensing Receptor Gene in respect to Survival of Hemodialysis Patients: A Prospective Observational Study
Table 3
Statistical significance of differences in all-cause mortality evaluated by the Kaplan-Meier analysis for vitamin D signaling pathway genes and CASR in hemodialysis patients undergoing the 7-year prospective study.
Tested polymorphism
Major homozygotes versus heterozygotes versus minor homozygotes
Dominant model of inheritance
Recessive model of inheritance
Additive model of inheritance
GC rs7041
458
GG versus GT versus TT
TT + GT versus GG
TT versus GT + GG
TT versus GG
GC rs1155563
472
TT versus CT versus CC
CC + CT versus TT
CC versus CT + TT
CC versus TT
GC rs2298849
472
TT versus CT versus CC
CC + CT versus TT
CC versus CT + TT
CC versus TT
RXRA rs10881578
472
AA versus AG versus GG
GG + AG versus AA
GG versus AG + AA
GG versus AA
RXRA rs10776909
472
CC versus CT versus TT
TT + CT versus CC
TT versus CT + CC
TT versus CC
RXRA rs749759
464
GG versus AG versus AA
AA + AG versus GG
AA versus AG + GG
AA versus GG
VDR rs1544410
461
GG versus AG versus AA
AA + AG versus GG
AA versus AG + GG
AA versus GG
VDR rs2228570
449
CC versus CT versus TT
TT + CT versus CC
TT versus CT + CC
TT versus CC
CASR rs7652589
435
GG versus AG versus AA
AA + AG versus GG
AA versus AG + GG
AA versus GG
CASR: calcium-sensing receptor gene, GC: group-specific component gene, RXRA: retinoic X receptor alpha gene, and VDR: vitamin D receptor gene. Multiple-sample test . Log rank test .
