Research Article

Higher Serum Uric Acid Is Associated with Higher Bone Mineral Density in Chinese Men with Type 2 Diabetes Mellitus

Table 1

General characteristics of the study participants and comparison of characteristics according to serum UA tertiles.

Total ()Tertiles of serum uric acid level
Tertile 1 ()Tertile 2 ()Tertile 3 ()

Age (years)54.14 ± 11.4955.35 ± 11.6053.22 ± 10.8653.86 ± 11.930.155
Diabetes duration (years) 8.60 ± 6.458.86 ± 6.398.28 ± 6.468.67 ± 6.520.643
Height (cm)171.94 ± 5.65171.03 ± 5.83172.43 ± 5.52172.35 ± 5.500.018
Weight (kg)74.35 ± 12.9570.09 ± 11.3874.78 ± 12.8678.20 ± 13.28<0.001
BMI (kg/m2)25.08 ± 3.7323.91 ± 3.3425.09 ± 3.7126.25 ± 3.77<0.001
UA (mmol/L)0.34 ± 0.080.26 ± 0.030.33 ± 0.020.42 ± 0.05
Ca (mmol/L)2.21 ± 0.102.19 ± 0.122.22 ± 0.092.23 ± 0.100.002
PTH (pg/mL)48.16 ± 19.7545.21 ± 17.0748.51 ± 19.7150.75 ± 21.890.029
Cr mol/L)75.57 ± 20.3170.25 ± 18.7474.93 ± 15.3381.55 ± 24.31<0.001
vitD3 (nmol/L)38.21 ± 15.3338.57 ± 14.3436.59 ± 15.6339.42 ± 15.980.223
BMD
 L2–4 (g/cm2)1.20 ± 0.191.17 ± 0.181.21 ± 0.191.24 ± 0.180.001
 FN (g/cm2)0.95 ± 0.140.92 ± 0.120.95 ± 0.140.97 ± 0.14<0.001
 TH (g/cm2)1.01 ± 0.140.98 ± 0.131.02 ± 0.141.04 ± 0.15<0.001

Serum uric acid tertiles were as follows: tertile 1, 0.065–0.305 mmol/L; tertile 2, 0.306–0.367 mmol/L; tertile 3, 0.368–0.599 mmol/L. BMI: body mass index; UA: uric acid; Ca: serum calcium; PTH: parathyroid hormone; Cr: serum creatinine; vitD3: 25-OH vitamin D3; BMD: bone mineral density; L2–4: lumbar spine 2–4; FN: femoral neck; TH: total hip.