Research Article
Higher Serum Uric Acid Is Associated with Higher Bone Mineral Density in Chinese Men with Type 2 Diabetes Mellitus
Table 1
General characteristics of the study participants and comparison of characteristics according to serum UA tertiles.
| | Total () | Tertiles of serum uric acid level | | Tertile 1 () | Tertile 2 () | Tertile 3 () |
| Age (years) | 54.14 ± 11.49 | 55.35 ± 11.60 | 53.22 ± 10.86 | 53.86 ± 11.93 | 0.155 | Diabetes duration (years) | 8.60 ± 6.45 | 8.86 ± 6.39 | 8.28 ± 6.46 | 8.67 ± 6.52 | 0.643 | Height (cm) | 171.94 ± 5.65 | 171.03 ± 5.83 | 172.43 ± 5.52 | 172.35 ± 5.50 | 0.018 | Weight (kg) | 74.35 ± 12.95 | 70.09 ± 11.38 | 74.78 ± 12.86 | 78.20 ± 13.28 | <0.001 | BMI (kg/m2) | 25.08 ± 3.73 | 23.91 ± 3.34 | 25.09 ± 3.71 | 26.25 ± 3.77 | <0.001 | UA (mmol/L) | 0.34 ± 0.08 | 0.26 ± 0.03 | 0.33 ± 0.02 | 0.42 ± 0.05 | — | Ca (mmol/L) | 2.21 ± 0.10 | 2.19 ± 0.12 | 2.22 ± 0.09 | 2.23 ± 0.10 | 0.002 | PTH (pg/mL) | 48.16 ± 19.75 | 45.21 ± 17.07 | 48.51 ± 19.71 | 50.75 ± 21.89 | 0.029 | Cr mol/L) | 75.57 ± 20.31 | 70.25 ± 18.74 | 74.93 ± 15.33 | 81.55 ± 24.31 | <0.001 | vitD3 (nmol/L) | 38.21 ± 15.33 | 38.57 ± 14.34 | 36.59 ± 15.63 | 39.42 ± 15.98 | 0.223 | BMD | | | | | | L2–4 (g/cm2) | 1.20 ± 0.19 | 1.17 ± 0.18 | 1.21 ± 0.19 | 1.24 ± 0.18 | 0.001 | FN (g/cm2) | 0.95 ± 0.14 | 0.92 ± 0.12 | 0.95 ± 0.14 | 0.97 ± 0.14 | <0.001 | TH (g/cm2) | 1.01 ± 0.14 | 0.98 ± 0.13 | 1.02 ± 0.14 | 1.04 ± 0.15 | <0.001 |
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Serum uric acid tertiles were as follows: tertile 1, 0.065–0.305 mmol/L; tertile 2, 0.306–0.367 mmol/L; tertile 3, 0.368–0.599 mmol/L. BMI: body mass index; UA: uric acid; Ca: serum calcium; PTH: parathyroid hormone; Cr: serum creatinine; vitD3: 25-OH vitamin D3; BMD: bone mineral density; L2–4: lumbar spine 2–4; FN: femoral neck; TH: total hip.
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