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International Journal of Endocrinology
Volume 2016, Article ID 2930414, 8 pages
http://dx.doi.org/10.1155/2016/2930414
Clinical Study

Valproic Acid, a Histone Deacetylase Inhibitor, in Combination with Paclitaxel for Anaplastic Thyroid Cancer: Results of a Multicenter Randomized Controlled Phase II/III Trial

1Department of Medical Sciences, University of Turin, Turin, Italy
2Oncological Endocrinology, A.O.U. “Città della Salute e della Scienza di Torino” Hospital, Turin, Italy
3Transition Unit for Childhood Cancer Survivors, A.O.U. “Città della Salute e della Scienza di Torino” Hospital, Turin, Italy
4Department of Drug Science and Technology, University of Turin, Turin, Italy
5Section of Endocrinology, Division of Internal Medicine, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy
6Endocrinology, Diabetes, and Metabolism Unit, A.O. Ordine Mauriziano di Torino, “Umberto I” Hospital, Turin, Italy

Received 30 June 2016; Accepted 8 September 2016

Academic Editor: Carlo Cappelli

Copyright © 2016 Maria Graziella Catalano et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [7 citations]

The following is the list of published articles that have cited the current article.

  • Qian Tong, Yang Zheng, Qiuju Liu, Shao-Yu Chen, Jian Sun, Zheng Xu, Lu Cai, Zhiguo Zhang, Shudong Wang, and Ling-Bo Qian, “Inhibition of HDAC3 prevents diabetic cardiomyopathy in OVE26 mice via epigenetic regulation of DUSP5-ERK1/2 pathway,” Clinical Science, vol. 131, no. 15, pp. 1841–1857, 2017. View at Publisher · View at Google Scholar
  • Subbroto Saha, Yingfu Yin, Kyeongseok Kim, Gwang-Mo Yang, Ahmed Dayem, Hye Choi, and Ssang-Goo Cho, “Valproic Acid Induces Endocytosis-Mediated Doxorubicin Internalization and Shows Synergistic Cytotoxic Effects in Hepatocellular Carcinoma Cells,” International Journal of Molecular Sciences, vol. 18, no. 5, pp. 1048, 2017. View at Publisher · View at Google Scholar
  • S. R. Priya, Chandra Shekhar Dravid, Raghunadharao Digumarti, and Mitali Dandekar, “Targeted Therapy for Medullary Thyroid Cancer: A Review,” Frontiers in Oncology, vol. 7, 2017. View at Publisher · View at Google Scholar
  • Ernestina Marianna De Francesco, Federica Sotgia, Michael P. Lisanti, Marcello Maggiolini, and Herbert B. Tanowitz, “Targeting hypoxic cancer stem cells (CSCs) with Doxycycline: Implications for optimizing anti-angiogenic therapy,” Oncotarget, vol. 8, no. 34, pp. 56126–56142, 2017. View at Publisher · View at Google Scholar
  • Hayley Heers, Jennifer Stanislaw, John Harrelson, and Michael W. Lee, “Valproic acid as an adjunctive therapeutic agent for the treatment of breast cancer,” European Journal of Pharmacology, vol. 835, pp. 61–74, 2018. View at Publisher · View at Google Scholar
  • George E. Naoum, Michael Morkos, Brian Kim, and Waleed Arafat, “Novel targeted therapies and immunotherapy for advanced thyroid cancers,” Molecular Cancer, vol. 17, no. 1, 2018. View at Publisher · View at Google Scholar
  • Shikha Saini, Kiara Tulla, Ajay V. Maker, Kenneth D. Burman, and Bellur S. Prabhakar, “Therapeutic advances in anaplastic thyroid cancer: a current perspective,” Molecular Cancer, vol. 17, no. 1, 2018. View at Publisher · View at Google Scholar