Thyroid Stimulating Hormone Is Increased in Hypertensive Patients with Obstructive Sleep Apnea
Table 1
Comparison of demographic characteristics and polysomnographic and biochemical parameters between non-OSA and mild to severe OSA subjects.
Non-OSA
Mild OSA
Moderate OSA
Severe OSA
Gender (M/F)
87/57
95/54
86/26
95/17
Age (years)
42.39 ± 9.15
45.89 ± 9.59
48.22 ± 10.02
46.66 ± 8.61
BMI (kg/m2)
26.62 ± 3.50
28.00 ± 4.20
28.28 ± 3.81
29.72 ± 3.96
SBP (mmHg)
137.10 ± 18.35
138.81 ± 19.41
140.04 ± 19.54
144.41 ± 18.24
DBP (mmHg)
93.11 ± 11.90
94.09 ± 13.68
94.93 ± 14.48
98.73 ± 13.68
LnAHI (events/h)
0.35 ± 0.96
2.14 ± 0.31
3.05 ± 0.19
3.91 ± 0.33
LnLSaO2 (%)
4.46 ± 0.11
4.39 ± 0.07
4.33 ± 0.08
4.16 ± 0.24
LnODI3 (events/h)
2.54 ± 0.64
3.33 ± 0.39
3.80 ± 0.36
4.38 ± 0.26
LnODI4 (events/h)
1.55 ± 0.89
2.73 ± 0.49
3.43 ± 0.34
4.20 ± 0.31
LnTSH (μIU/mL)
0.74 ± 0.77
0.87 ± 0.76
0.83 ± 0.75
0.99 ± 0.81
FT3 (pg/mL)
3.54 ± 1.56
3.25 ± 0.75
4.99 ± 3.44
4.01 ± 4.20
FT4 (ng/dL)
6.60 ± 6.37
6.12 ± 6.94
7.70 ± 8.10
7.28 ± 8.56
TT3 (ng/mL)
1.40 ± 0.35
1.41 ± 1.74
1.40 ± 0.40
1.38 ± 0.49
TT4 (ng/mL)
39.96 ± 40.08
35.03 ± 31.91
41.31 ± 40.87
40.01 ± 39.07
ATG (IU/mL)
10.02
10.89
11 (6.56)
11
TPO (IU/mL)
10
9.09 (16.05)
10
9.82
LnALT (U/L)
3.26 ± 0.56
3.30 ± 0.58
3.23 ± 0.46
3.40 ± 0.52
LnAST (U/L)
3.01 ± 0.41
3.03 ± 0.40
2.98 ± 0.35
3.11 ± 0.42
LnGLT (U/L)
3.42 ± 0.67
3.57 ± 0.69
3.60 ± 0.71
3.77 ± 0.71
LnCr (μmol/L)
4.20 ± 0.33
4.20 ± 0.24
4.25 ± 0.23
4.27 ± 0.24
LnBUN (mmol/L)
1.62 ± 0.27
1.62 ± 0.24
1.69 ± 0.26
1.70 ± 0.38
LnHs-CRP (mg/L)
0.068 ± 1.09
0.32 ± 0.95
0.15 ± 0.99
0.52 ± 1.01
FBG (mmol/L)
4.99 ± 0.77
5.13 ± 1.33
5.27 ± 1.49
5.66 ± 1.88
Control versus mild OSA; control versus moderate OSA; control versus severe OSA; mild versus moderate OSA; mild versus severe OSA; moderate versus severe OSA. Significance: . BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; AHI: apnea hypopnea index; LSaO2: lowest saturation of oxygen; ODI3: oxygen desaturation index of 3%; ODI4: oxygen desaturation index of 4%; FBG: fasting blood glucose; ALT: alanine aminotransferase; AST: aspartate transaminase; GLT: glutamic transaminase; Cr: creatinine; BUN: blood urea nitrogen; Hs-CRP: high-sensitivity C-reactive protein; TSH: thyroid stimulating hormone; FT3: free triiodothyronine; FT4: free thyroxine; ATG: thyroglobulin; TPO: thyroid peroxidase.
