Intrahepatic Fat Content and Markers of Hepatic Fibrosis in Obese Children

Table 2

Comparison of biochemical parameters.

Parameters	SOB ( = 75)	SS ( = 49)	NASH ( = 65)
ALT (U/L)	18 (14–23); (4–114)	37 (29.5–43.5); (17–50)	96 (69.5–137); (51–370)
AST (U/L)	23 (20–26); (12–74)	28 (24.5–32); (18–102)	51 (41–75.5); (27–293)
γ-GT (U/L)	16 (13–21); (7–71)	23 (19.5–28); (2–71)	42 (28.5–65); (17–138)
TG (mmol/L)	0.95 (0.82–1.39); (0.39–3.69)	1.33 (0.94–1.77); (0.4–3.86)	1.43 (0.93–1.80); (0.65–4.69)
CHOL (mmol/L)	4.28 ± 0.71; (3.09–6.25)	4.32 ± 0.86; (2.54–6.55)	4.59 ± 0.98; (1.14–7.73)
HDL (mmol/L)	1.27 ± 0.37; (0.77–2.71)	1.17 ± 0.31; (0.58–1.79)	1.05 ± 2.63; (0.57–1.66)
LDL (mmol/L)	2.32 ± 0.53; (1.07–3.91)	2.44 ± 0.64; (1.19–4.09)	2.61 ± 0.55; (1.3–3.85)
Uric acid (µmol/L)	346.02 ± 80.3; (201.9–586.4)	392.14 ± 74.05; (253.1–568.5)	429.38 ± 90.72; (226.7–673.6)
HA (ng/mL)	59.56 (40.22–81.6); (16–183)	60.14 (49.7–88.53); (9–130)	71.7 (53.04–94.02); (16–166)
CIV (ng/mL)	78.79 ± 27.77; (48–135)	82.20 ± 32.40; (53–118)	85.49 ± 27.76; (46–132)
PCIII (ng/mL)	173.14 (133.94–217.14); (73–299)	161.5 (138.44–198.20); (81–368)	195.1 (153.75–258.58); (106–462)
LN (ng/mL)	128.90 ± 21.17; (67–195)	128.99 ± 17.55; (73–178)	126.34 ± 30.71; (14–214)
NFS	−5.57 ± 1.34; (−7.94–−1.11)	−5.50 ± 1.33; (−8.63–−0.94)	−5.29 ± 1.23; (−6.45–−0.32)
APRI	0.125 (0.10–0.16); (0.06–0.41)	0.16 (0.14–0.18); (0.08–0.7)	0.33 (0.23–0.45); (0.15–1.78)
FIB-4	0.17 (0.12–0.23); (0.08–0.56)	0.15 (0.13–0.17); (0.07–0.71)	0.19 (0.16–0.26); (0.07–0.64)
HbA1c (%)	5.76 ± 0.41; (4.9–7.0)	5.90 ± 0.49; (4.8–6.9)	5.85 ± 0.39; (4.9–6.8)
Insulin 0 (µIU/mL)	16.10 (12.38–22.38); (0.8–46.1)	19.9 (13.85–31.15); (1.3–64.3)	21.60 (14.40–30.30); (0.9–56.9)
Insulin 120 (µIU/mL)	53.10 (30.10–81.40); (1.9–174.2)	73.10 (29.15–119.85); (2.4–300)	78.80 (29.50–144.65); (2.1–300)
OGTT 120 (mmol/L)	6.50 (5.10–11.10); (5.1–11.1)	6.70 (6025–7.40); (5.4–10)	7.30 (6.40–7.90); (5–18.8)
FG (mmol/L)	5.40 (5.10–5.70); (4.3–7.7)	5.40 (4.40–8.90); (4.4–8.9)	5.50 (5.25–5.75); (4.1–8)
HOMA-IR	3.79 (2.85–5.08); (0.18–10.65)	4.77 (3.37–7.06); (0.31–24.29)	5.03 (3.58–7.48); (0.23–15.17)

Compared with SOB,  and ; compared to SS,  and .
Quantitative data with normal distribution are expressed as the mean ± SD, and variables with skewed distribution are presented as median with interquartile range. The ranges of all the parameters were listed in the bracket.